Commentary: William Budd on cholera

William Budd

"The idea that phthisis is a self-propagated zymotic disease, and that all the leading phenomena of its distribution may be explained by supposing that it is disseminated through society by specific germs contained in the tuberculous matter cast off by persons already suffering from the disease, first came to my mind, unbidden, so to speak, while I was walking on the Observatory Hill at Clifton...

The William Budd Health Centre

William Farr, The Lancet, and epidemic cholera.

In 1867 William Farr published his report into the cholera epidemic which, in 1866, had killed over five thousand people living in the Whitechapel area of East London. It was the last of the four epidemics which ravaged the capital in the mid-nineteenth century [1]. Farr, after an early career writing for The Lancet under its founding editor Thomas Wakley, had been appointed ‘compiler of abstra...

Commentary on William Summers Paper on Tacrine March 6, 2000.

The cholinergic dysfunction in AD is not necessarily predominant (1,4,5) and responsivity to a cholinesterase inhibitor is not diagnostic for Alzheimer’s disease. Normal young people have improved on psychometric measures in memory and attention after physostigmine challenge (3). Additionally, postmortem neurochemical measures of cholinergic function in AD patients do not correlate with ante mo...

Commentary: two views of cholera.

Edmund Parkes was a well-qualified choice to provide a critical assessment 1 of John Snow's second edition of the Mode of Communication of Cholera 2 in the British and Foreign Medico-Chirurgical Review. A former military surgeon, Parkes had extensive experience of cholera in Asia. His monograph, Researches into the Pathology and Treatment of the Algide or Asiatic Cholera, 3 had been published i...